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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
10.61
Human Site:
S524
Identified Species:
17.95
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S524
T
G
L
F
R
S
S
S
G
S
G
V
Q
P
D
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S524
T
G
L
F
R
S
S
S
G
S
G
V
Q
P
D
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
S525
T
E
L
F
R
S
S
S
G
S
G
V
H
T
D
Dog
Lupus familis
XP_539054
796
87704
G516
A
G
L
L
P
G
R
G
P
R
G
S
T
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
G523
P
V
L
L
R
S
R
G
D
S
C
G
H
A
E
Rat
Rattus norvegicus
Q2KJ09
826
93743
E528
M
I
E
S
A
A
D
E
R
K
C
P
E
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
S518
E
G
S
V
D
A
D
S
E
A
S
E
W
E
S
Chicken
Gallus gallus
O57429
357
40913
W78
A
K
L
I
Q
L
L
W
T
S
S
P
N
D
S
Frog
Xenopus laevis
Q6PAW2
901
101274
T508
T
M
E
T
D
L
S
T
L
E
N
G
N
E
E
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
A535
E
P
E
Q
E
Q
A
A
S
V
N
N
R
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
D538
Y
L
Q
L
S
T
K
D
N
I
S
L
V
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
G552
C
S
E
Q
T
A
A
G
D
V
G
I
G
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
F629
Y
V
D
F
S
S
F
F
D
E
P
E
I
S
E
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
E193
A
L
D
K
I
V
H
E
L
Y
G
A
L
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
80
20
N.A.
26.6
0
N.A.
13.3
13.3
13.3
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
80
20
N.A.
33.3
13.3
N.A.
26.6
20
26.6
20
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
8
22
15
8
0
8
0
8
0
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% C
% Asp:
0
0
15
0
15
0
15
8
22
0
0
0
0
8
22
% D
% Glu:
15
8
29
0
8
0
0
15
8
15
0
15
8
15
22
% E
% Phe:
0
0
0
29
0
0
8
8
0
0
0
0
0
8
0
% F
% Gly:
0
29
0
0
0
8
0
22
22
0
43
15
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
15
8
0
% H
% Ile:
0
8
0
8
8
0
0
0
0
8
0
8
8
0
0
% I
% Lys:
0
8
0
8
0
0
8
0
0
8
0
0
0
0
0
% K
% Leu:
0
15
43
22
0
15
8
0
15
0
0
8
8
0
15
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
15
8
15
8
0
% N
% Pro:
8
8
0
0
8
0
0
0
8
0
8
15
0
15
8
% P
% Gln:
0
0
8
15
8
8
0
0
0
0
0
0
15
8
0
% Q
% Arg:
0
0
0
0
29
0
15
0
8
8
0
0
8
0
0
% R
% Ser:
0
8
8
8
15
36
29
29
8
36
22
8
0
15
15
% S
% Thr:
29
0
0
8
8
8
0
8
8
0
0
0
8
8
15
% T
% Val:
0
15
0
8
0
8
0
0
0
15
0
22
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _